July 2020: CryoCrate LLC won a Competitive Administrative Supplement for our ongoing NIH SBIR phase II Award.

This award is an administrative supplementary support for our ongoing SBIR Phase II award, to address the special NIH RFA for “NOT-AG-20-008, Alzheimer’s-focused administrative supplements for NIH grants that are not focused on Alzheimer’s disease” from NAI. The project aims to modify the design of the INSTAvitria™ system to achieve vitrification cryopreservation of 3D central nervous system cell constructs that are used as models for drug discovery in Alzheimer’s disease and other neural degenerative symptoms and as an emerging clinical strategy for associated new cyto-therapies. This approach will remove the need for any toxic cryoprotectant for cryopreservation of these tissues and significantly minimize tissue damage caused by traditional cryopreservation methods.